Mexican voters are expected to make history Sunday by electing their first woman president.
Ruling party candidate Claudia Sheinbaum, a former Mexico City mayor and a scientist by training, had a 17 percentage point lead over her main opposition rival Xochitl Galvez on the eve of the vote.
The only man running, centrist Jorge Alvarez Maynez, was trailing far behind.
The turn of event shows a woman is almost certain to break the highest political glass ceiling in Mexico.
That prospect motivates other women to succeed and to think "yes you can," said Blanca Sosa, a 31-year-old store worker in Mexico City.
She expects Sheinbaum to continue the "good things" done by outgoing President Andres Manuel Lopez Obrador, such as pensions for the elderly and an increased minimum wage.
Ricardo Sanchez, however, said he planned to vote for Galvez because of her "business vision."
Lopez Obrador's "policy of putting the poor first is to ruin us all so that we're poor and then he gives to us," the 55-year-old businessman said in the northern city of Monterrey.
Sheinbaum, 61, owes much of her popularity to Lopez Obrador, a fellow leftist and mentor who has an approval rating of more than 60 percent but is only allowed to serve one term.